Endocannabinoid system

The endocannabinoid system (ECS) is a crucial molecular signaling network that helps regulate many vital functions in the body and brain. It comprises cannabinoid receptors, endogenous endocannabinoid compounds produced naturally within the body, and related metabolic enzymes distributed throughout the central and peripheral nervous systems.

Cannabinoid receptors respond to endocannabinoids synthesized internally as well as plant-based cannabinoids like THC and CBD from cannabis. Different exogenous cannabinoids will interact with the endocannabinoid system's CB1 and CB2 receptors uniquely, leading to their wide range of effects.

As the system tasked with maintaining homeostasis and health throughout the body, the ECS plays a pivotal role in hunger, digestion, pain management, mood, memory, reproduction, stress response, sleep cycles, immune function, and more. Understanding this critical network sheds light on how cannabis and cannabinoids exert their influence on so many physiological processes and afflictions.