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CBLA (cannabicyclolic acid)

Alana Rossi
August 19, 2023

CBLA (cannabicyclolic acid) is a rarely occurring, non-intoxicating minor cannabinoid formed when CBCA (the acidic precursor of CBD) degrades and transforms into CBL due to exposure to light or heat over time during storage or processing of high-CBD cannabis plants.

Because modern cannabis research has only emerged from heavy restrictions in the past couple decades, scientific understanding and awareness of minor and rare cannabinoids like CBLA remains extremely limited. However, initial preclinical research in cell and animal models suggests CBLA carries promise as an anti-inflammatory and analgesic compound.

While widespread consumer access and knowledge of ultra-minor cannabinoids like CBLA is currently scarce, the burgeoning growth of interest, resources, and technologies surrounding minor cannabinoids will continue opening new doors for investigating the as yet unknown capabilities of little-studied compounds like CBLA beyond the two major cannabinoids THC and CBD that dominate the market and research today.

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